BDBM357253 (5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl)-1H-pyrazol-4-yl)(6-(1-ethyl-1H-pyrazol-4-yl)-1H-indol-2-yl)methanone::US10214515, Example 16
SMILES CCn1cc(cn1)-c1ccc2cc([nH]c2c1)C(=O)c1cnn(c1N)-c1ccc2[nH]c(nc2c1)C1CC1
InChI Key InChIKey=LGWVEHCWSZKUPK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 357253
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 4.90nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 280nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 6.80nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 0.700nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair