BDBM357305 US10214519, Example 31
SMILES Fc1ccc2c(ccnc2c1Cl)-n1c(CC2CC2)nc2c(cc(cc12)N1CCOCC1)-c1nnc[nH]1
InChI Key InChIKey=ZBDWAQNCYHCCJS-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 357305
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 9nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair