BDBM357522 US10214519, Example 278
SMILES Cc1nc2c(cc(cc2n1-c1ccnc2c(Cl)cccc12)N1CCOCC1)-c1cnc(Cl)[nH]1
InChI Key InChIKey=NHYJZQIBQGUJSD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 357522
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 4nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair