BDBM357654 7-(3- (trifluorometh- yl)benzyl)-3H- [1,2,3]triazolo [4,5-b]pyridin- 5-amine::US10214527, Example 26
SMILES Nc1cc(Cc2cccc(c2)C(F)(F)F)c2nn[nH]c2n1
InChI Key InChIKey=OULGOWJVPMGCES-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 357654
Affinity DataIC50: 5.50E+3nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 683nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair