BDBM357758 KM-05-100/(I-11)::US10214530, Example 11
SMILES Cn1c2nc(Cc3nc4ccc(Br)cc4[nH]3)n(Cc3ccccc3)c2c(=O)[nH]c1=O
InChI Key InChIKey=YAWZRUWHTCJPCU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 357758
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 740nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 4.14E+3nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair