BDBM358663 3-(2-(4-(3-(4-amino-5-chloropyrrolo [2,1-f][1,2,4]triazin-7-yl)phenyl)-2,2- dimethyl-3-oxopiperazin-1-yl)-2- oxoethyl)oxazolidin-2-one::US10214537, Example 740

SMILES CC1(C)N(CCN(C1=O)c1cccc(c1)-c1cc(Cl)c2c(N)ncnn12)C(=O)CN1CCOC1=O

InChI Key InChIKey=KKPIFVUMLXYYJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358663   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM358663(3-(2-(4-(3-(4-amino-5-chloropyrrolo [2,1-f][1,2,4]...)
Affinity DataIC50:  0.5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent