BDBM358903 (6R,8aS)-6-(8-amino-1- {2-methoxy-4-[(1S)- 2,2,2-trifluoro-1- hydroxy-1- phenylethyl]phenyl} imidazo[1,5-a]pyrazin-3- yl)hexahydroindolizin- 3(2H)-one::US10214546, Example 34
SMILES COc1cc(ccc1-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2ccnc(N)c12)C(O)(c1ccccc1)C(F)(F)F
InChI Key InChIKey=GBYVZSVHGHPHSN-IEYUPOKRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358903
Affinity DataIC50: 0.740nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair