BDBM359188 US10220048, Compound AA98::US10952992, No. AA98::US11413242, Compound AA98::US11666558, Example AA98
SMILES OS(=O)(=O)Nc1ccc(C[C@H](Nc2nnc(Cc3ccccc3)s2)c2csc(n2)-c2cccs2)cc1
InChI Key InChIKey=MMYLSMYTNAHPDC-IBGZPJMESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 359188
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics
US Patent
Aerpio Therapeutics
US Patent
Affinity DataIC50: 0.600nMAssay Description:HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., “Design and Synthesis of Potent, N...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics
US Patent
Aerpio Therapeutics
US Patent
Affinity DataIC50: 0.600nMAssay Description:Non-limiting examples of the HPTP-β IC50(μM) activity for illustrative compounds are listed in TABLE 2.More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics
US Patent
Aerpio Therapeutics
US Patent
Affinity DataIC50: 0.600nMAssay Description:Non-limiting examples of the HPTPβ IC50 (μM) activity.More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics
US Patent
Aerpio Therapeutics
US Patent
Affinity DataIC50: 0.600nMAssay Description:Non-limiting examples of the HPTP-β IC50 (μM) activity.More data for this Ligand-Target Pair