BDBM35954 4-pyridinoxy-2-anilinopyridine-based compound, 18

SMILES Cc1cc(Oc2ccnc(Nc3ccc(F)cc3)c2)c(nc1C)-c1ccccn1

InChI Key InChIKey=GEDJWDMJHOZAHV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35954   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM35954(4-pyridinoxy-2-anilinopyridine-based compound, 18)
Affinity DataIC50:  129nM EC50:  63nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization assay was used to assess the ALK5 binding capacity and biochemical activity of compounds. ALK5 protein was added to each ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed