BDBM359540 4-[(6R or S)-1-({2- chloro-6-[1- (trifluoromethyl)cyclo- propyl]phenyl}car- bonyl)-6-(5-oxa-2- azaspiro[3.4]oct-2- ylcarbonyl)-4,5,6,7- tetrahydro-1H- indazol-3-yl]-3- fluorobenzoic acid::US10221142, Example 21F
SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C3(CC3)C(F)(F)F)c3CC(CCc23)C(=O)N2CC3(C2)CCCO3)c(F)c1
InChI Key InChIKey=MZRIMTOGJBQVLU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 359540
Affinity DataIC50: 0.700nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair