BDBM359754 7-Bromo-2,2-dimethyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-2,3-dihydrobenzofuran-5-carboxamide::US9822103, Example 24

SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc2CC(C)(C)Oc2c(Br)c1

InChI Key InChIKey=YHBWCGRJPAGCLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359754   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM359754(7-Bromo-2,2-dimethyl-N-((6-methyl-2-oxo-4-propyl-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent