BDBM359758 N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-7-(4-(morpholinomethyl)phenyl)-2,3-dihydrobenzofuran-5-carboxamide::US9822103, Example 28

SMILES CC1COc2c1cc(cc2-c1ccc(CN2CCOCC2)cc1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359758   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM359758(N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: >1.00E+3nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent