BDBM359775 9-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-4-methyl-2,5-dihydrobenzo[b]oxepine-7-carboxamide::US9822103, Example 44

SMILES Cc1cc(C)c(CNC(=O)c2cc(Br)c3OCC=C(C)Cc3c2)c(=O)[nH]1

InChI Key InChIKey=FKDNRFGIZCNPMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359775   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM359775(9-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM359775(9-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent