BDBM359809 US9822103, Example 69::rac-(3aS,8bS)-5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3a,6-dimethyl-2, 3,3a, 8b-tetrahydro-1H-cyclopenta[b]benzofuran-7-carboxamide

SMILES Cc1cc(C)c(CNC(=O)c2cc3[C@@H]4CCC[C@]4(C)Oc3c(Br)c2C)c(=O)[nH]1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359809   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM359809(US9822103, Example 69 | rac-(3aS,8bS)-5-Bromo-N-((...)
Affinity DataIC50: <500nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent