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BDBM360045 3',5-Difluoro-::US9828339, Example 17

SMILES: CN1CCCC1CCOC(=O)Nc1ccc(F)cc1-c1cccc(Cl)c1

InChI Key: InChIKey=MPWJLCITBXRLFD-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360045   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360045
PNG
(3',5-Difluoro- | US9828339, Example 17)
Show SMILES CN1CCCC1CCOC(=O)Nc1ccc(F)cc1-c1cccc(Cl)c1
Show InChI InChI=1/C20H22ClFN2O2/c1-24-10-3-6-17(24)9-11-26-20(25)23-19-8-7-16(22)13-18(19)14-4-2-5-15(21)12-14/h2,4-5,7-8,12-13,17H,3,6,9-11H2,1H3,(H,23,25)
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PC sid
UniChem
Article
US Patent
1n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair