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BDBM360182 (S)-(1-methylpyrrolidin-3-yl)-methyl(3'-methyl-[1,1'-biphenyl]-2-yl)carbamate::US9828339, Example 101

SMILES: CN1CC[C@H](COC(=O)Nc2ccccc2-c2cccc(C)c2)C1

InChI Key: InChIKey=YZYIKHZARARQGL-XISACWJONA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360182   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360182
PNG
((S)-(1-methylpyrrolidin-3-yl)-methyl(3'-methyl-[1,...)
Show SMILES CN1CC[C@H](COC(=O)Nc2ccccc2-c2cccc(C)c2)C1
Show InChI InChI=1/C20H24N2O2/c1-15-6-5-7-17(12-15)18-8-3-4-9-19(18)21-20(23)24-14-16-10-11-22(2)13-16/h3-9,12,16H,10-11,13-14H2,1-2H3,(H,21,23)/t16-/s2
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PC cid
PC sid
UniChem
Article
US Patent
3.79n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair