BindingDB logo
myBDB logout

BDBM360258 (S)-(1-methyl-::US9828339, Example 165

SMILES: CN1CCC[C@H]1COC(=O)Nc1ccccc1-c1cccc(Cl)c1

InChI Key: InChIKey=WBXRAAVXXMXBBR-XISACWJONA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360258   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360258
PNG
((S)-(1-methyl- | US9828339, Example 165)
Show SMILES CN1CCC[C@H]1COC(=O)Nc1ccccc1-c1cccc(Cl)c1
Show InChI InChI=1/C19H21ClN2O2/c1-22-11-5-8-16(22)13-24-19(23)21-18-10-3-2-9-17(18)14-6-4-7-15(20)12-14/h2-4,6-7,9-10,12,16H,5,8,11,13H2,1H3,(H,21,23)/t16-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
0.630n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair