BindingDB logo
myBDB logout

BDBM360285 (S)-(1-methyl-::US9828339, Example 190

SMILES: CN1CCC[C@H]1COC(=O)Nc1ccccc1-c1cc(Cl)ccc1F

InChI Key: InChIKey=SMZDVJZOFXDEOH-YQTOOIBONA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360285   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360285
PNG
((S)-(1-methyl- | US9828339, Example 190)
Show SMILES CN1CCC[C@H]1COC(=O)Nc1ccccc1-c1cc(Cl)ccc1F
Show InChI InChI=1/C19H20ClFN2O2/c1-23-10-4-5-14(23)12-25-19(24)22-18-7-3-2-6-15(18)16-11-13(20)8-9-17(16)21/h2-3,6-9,11,14H,4-5,10,12H2,1H3,(H,22,24)/t14-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
2.17n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair