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BDBM360287 (R)-(1-methyl-::US9828339, Example 192

SMILES: CN1CC[C@@H](COC(=O)Nc2ccc(F)cc2-c2cccc(C)c2)C1

InChI Key: InChIKey=UHEILDGIYHFQOF-GGYSOQFKNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360287   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360287
PNG
((R)-(1-methyl- | US9828339, Example 192)
Show SMILES CN1CC[C@@H](COC(=O)Nc2ccc(F)cc2-c2cccc(C)c2)C1
Show InChI InChI=1/C20H23FN2O2/c1-14-4-3-5-16(10-14)18-11-17(21)6-7-19(18)22-20(24)25-13-15-8-9-23(2)12-15/h3-7,10-11,15H,8-9,12-13H2,1-2H3,(H,22,24)/t15-/s2
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PC cid
PC sid
UniChem
Article
US Patent
4.60n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair