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BDBM360290 (R)-(1-methyl-::US9828339, Example 195

SMILES: CN1CC[C@@H](COC(=O)Nc2ccc(F)cc2-c2cccc(Cl)c2)C1

InChI Key: InChIKey=MVZVRMKBJUPMRQ-CYBMUJFWSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360290   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360290
PNG
((R)-(1-methyl- | US9828339, Example 195)
Show SMILES CN1CC[C@@H](COC(=O)Nc2ccc(F)cc2-c2cccc(Cl)c2)C1
Show InChI InChI=1S/C19H20ClFN2O2/c1-23-8-7-13(11-23)12-25-19(24)22-18-6-5-16(21)10-17(18)14-3-2-4-15(20)9-14/h2-6,9-10,13H,7-8,11-12H2,1H3,(H,22,24)/t13-/m1/s1
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PC cid
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Article
US Patent
1.08n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair