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BDBM360294 (S)-(1-methyl-::US9828339, Example 199

SMILES: CN1CCC[C@H]1COC(=O)Nc1ccccc1-c1cccc(C)c1

InChI Key: InChIKey=CUWCIUNJZHEGTQ-AGDOHHJYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360294   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360294
PNG
((S)-(1-methyl- | US9828339, Example 199)
Show SMILES CN1CCC[C@H]1COC(=O)Nc1ccccc1-c1cccc(C)c1
Show InChI InChI=1/C20H24N2O2/c1-15-7-5-8-16(13-15)18-10-3-4-11-19(18)21-20(23)24-14-17-9-6-12-22(17)2/h3-5,7-8,10-11,13,17H,6,9,12,14H2,1-2H3,(H,21,23)/t17-/s2
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PC cid
PC sid
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Article
US Patent
0.800n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair