BDBM360401 US9828368, Example 54

SMILES CCOC(=O)C(NC(=O)[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1)C(O)(O)C(F)(F)F

InChI Key InChIKey=ZTWIEFDVQIHPNO-LJNCCCJHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360401   

TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360401(US9828368, Example 54)
Affinity DataIC50:  240nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360401(US9828368, Example 54)
Affinity DataIC50:  42nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent