BDBM360538 US9828369, Example 95::tert-butyl 3-(2-(((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)amino)-2-oxoethyl)-3- phenylpyrrolidine-1-carboxylate

SMILES COc1cccc(c1)-c1ccc(CNC(=O)CC2(CCN(C2)C(=O)OC(C)(C)C)c2ccccc2)c2cnccc12

InChI Key InChIKey=HIMHBDPSXJECIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360538   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360538(US9828369, Example 95 | tert-butyl 3-(2-(((5-(3- m...)
Affinity DataIC50:  1.31E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent