BDBM360577 2-([1,1'-biphenyl]-4-yl)-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)propanamide::US9828369, Example 134

SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc(cc2)-c2ccccc2)c2cnccc12

InChI Key InChIKey=IALZKGPMOVMQPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360577   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360577(2-([1,1'-biphenyl]-4-yl)-N-((5-(3- methoxyphenyl)i...)
Affinity DataIC50:  324nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent