BDBM360582 2-(2-fluorophenyl)-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)propanamide::US9828369, Example 139

SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccccc2F)c2cnccc12

InChI Key InChIKey=JPAVSGMNXFJBEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360582   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360582(2-(2-fluorophenyl)-N-((5-(3- methoxyphenyl)isoquin...)
Affinity DataIC50:  213nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent