BDBM360601 1-(2,3-dichlorophenyl)-3-((5-(1- phenylyinyl)isoquinolin-8-yl)methyl)urea::US9828369, Example 158

SMILES Clc1cccc(NC(=O)NCc2ccc(C(=C)c3ccccc3)c3ccncc23)c1Cl

InChI Key InChIKey=RONPKBDBWHQUTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360601   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360601(1-(2,3-dichlorophenyl)-3-((5-(1- phenylyinyl)isoqu...)
Affinity DataIC50:  374nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent