BDBM360602 1-(2,3-dichlorophenyl)-3-((5-(3- methoxypropyl)isoquinolin-8- yl)methyl)urea::US9828369, Example 159

SMILES COCCCc1ccc(CNC(=O)Nc2cccc(Cl)c2Cl)c2cnccc12

InChI Key InChIKey=IYHJUZKUMYDDMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360602   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360602(1-(2,3-dichlorophenyl)-3-((5-(3- methoxypropyl)iso...)
Affinity DataIC50:  478nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent