BDBM360855 4-(2-aminobenzo[d]oxazol- 4-yl)-N1-(2-aminoethyl)-3- (2H-tetrazol-5-yl)benzene- 1,2-disulfonamide::US10221163, Example 11

SMILES NCCNS(=O)(=O)c1ccc(-c2cccc3oc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=CJZITJYNLXIFBE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 360855   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360855(4-(2-aminobenzo[d]oxazol- 4-yl)-N1-(2-aminoethyl)-...)
Affinity DataIC50:  0.105nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360855(4-(2-aminobenzo[d]oxazol- 4-yl)-N1-(2-aminoethyl)-...)
Affinity DataIC50:  0.0500nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360855(4-(2-aminobenzo[d]oxazol- 4-yl)-N1-(2-aminoethyl)-...)
Affinity DataIC50:  0.0190nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent