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BDBM361344 3-methyl-N- (1H-pyrazolo[4,3-b] pyridin-3- yl)benzo[d]isothiazol- 5-amine::US10221172, Example 1

SMILES: Cc1nsc2ccc(Nc3n[nH]c4cccnc34)cc12

InChI Key: InChIKey=HIESXDJCMQHAIE-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM361344
PNG
(3-methyl-N- (1H-pyrazolo[4,3-b] pyridin-3- yl)benz...)
Show SMILES Cc1nsc2ccc(Nc3n[nH]c4cccnc34)cc12
Show InChI InChI=1S/C14H11N5S/c1-8-10-7-9(4-5-12(10)20-19-8)16-14-13-11(17-18-14)3-2-6-15-13/h2-7H,1H3,(H2,16,17,18)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 187n/an/an/an/a



Vanderbilt University

US Patent


Assay Description
In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...


US Patent US10221172 (2019)


Article DOI: 10.1021/jm070728r
More data for this
Ligand-Target Pair