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BDBM361360 (6-((1H-pyrazolo[4,3-b] pyridin-3-yl) amino)benzo[d]isothiazol- 3-yl)(1,4- oxazepan-4-yl)methanone::US10221172, Example 17

SMILES: O=C(N1CCCOCC1)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key: InChIKey=PQSAXJWNNWCBBX-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361360   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM361360
PNG
((6-((1H-pyrazolo[4,3-b] pyridin-3-yl) amino)benzo[...)
Show SMILES O=C(N1CCCOCC1)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12
Show InChI InChI=1S/C19H18N6O2S/c26-19(25-7-2-9-27-10-8-25)16-13-5-4-12(11-15(13)28-24-16)21-18-17-14(22-23-18)3-1-6-20-17/h1,3-6,11H,2,7-10H2,(H2,21,22,23)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 607n/an/an/an/a



Vanderbilt University

US Patent


Assay Description
In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...


US Patent US10221172 (2019)


Article DOI: 10.1021/jm070728r
More data for this
Ligand-Target Pair