BDBM361361 (6-((1H-pyrazolo [4,3-b]pyridin-3- yl)amino)benzo[d] isothiazol-3-yl)(3,5- dimethylpiperidin-1-yl) methanone::US10221172, Example 18
SMILES CC1CC(C)CN(C1)C(=O)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12
InChI Key
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 361361
Affinity DataEC50: 517nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
Affinity DataEC50: 447nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: 447nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair