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BDBM361380 2-(6-((1H-pyrazolo [4,3-b]pyridin- 3-yl)amino)benzo[d] isothiazol- 3-yl)propan-2-ol::US10221172, Example 38

SMILES: CC(C)(O)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key: InChIKey=HYBPDSUAUPYOSX-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361380   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM361380
PNG
(2-(6-((1H-pyrazolo [4,3-b]pyridin- 3-yl)amino)benz...)
Show SMILES CC(C)(O)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12
Show InChI InChI=1S/C16H15N5OS/c1-16(2,22)14-10-6-5-9(8-12(10)23-21-14)18-15-13-11(19-20-15)4-3-7-17-13/h3-8,22H,1-2H3,(H2,18,19,20)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 1.03E+3n/an/an/an/a



Vanderbilt University

US Patent


Assay Description
In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...


US Patent US10221172 (2019)


Article DOI: 10.1021/jm070728r
More data for this
Ligand-Target Pair