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BDBM361391 3-(piperidin-1- ylmethyl)-N-(1H- pyrazolo[3,4-b]pyridin-3- yl)isothiazolo[4,5-b] pyridin-6-amine::US10221172, Example 49

SMILES: C(N1CCCCC1)c1nsc2cc(Nc3n[nH]c4ncccc34)cnc12

InChI Key: InChIKey=CKNXLPBSTPQTTO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361391   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM361391
PNG
(3-(piperidin-1- ylmethyl)-N-(1H- pyrazolo[3,4-b]py...)
Show SMILES C(N1CCCCC1)c1nsc2cc(Nc3n[nH]c4ncccc34)cnc12
Show InChI InChI=1S/C18H19N7S/c1-2-7-25(8-3-1)11-14-16-15(26-24-14)9-12(10-20-16)21-18-13-5-4-6-19-17(13)22-23-18/h4-6,9-10H,1-3,7-8,11H2,(H2,19,21,22,23)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 1.56E+3n/an/an/an/a



Vanderbilt University

US Patent


Assay Description
In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...


US Patent US10221172 (2019)


Article DOI: 10.1021/jm070728r
More data for this
Ligand-Target Pair