BDBM361405 1-(4-(6-((1H-pyrazolo [3,4-b]pyrazin-3-yl) amino)benzo[d] isothiazol-3- yl)piperidin-1-yl)ethan- 1-one::US10221172, Example 63

SMILES CC(=O)N1CCC(CC1)c1nsc2cc(Nc3n[nH]c4nccnc34)ccc12

InChI Key InChIKey=WFUCKDVAIDPNQX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361405   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM361405(1-(4-(6-((1H-pyrazolo [3,4-b]pyrazin-3-yl) amino)b...)
Affinity DataEC50:  154nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent