BDBM361899 (R and S)-8-(1-ethyl-5-methyl- 1H-pyrazol-4-yl)-9-methyl-6-[1- (morpholin-4- ylcarbonyl)propoxy]-9H-purine::US10221178, Compound 1-1

SMILES CCC(Oc1ncnc2n(C)c(nc12)-c1cnn(CC)c1C)C(=O)N1CCOCC1

InChI Key InChIKey=FSGOGTIJEGGODG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361899   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361899((R and S)-8-(1-ethyl-5-methyl- 1H-pyrazol-4-yl)-9-...)
Affinity DataIC50:  320nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent