BDBM361935 9-ethyl-8-(2-methylpyrimidin-5- yl)-N-[(1S)-1-(4-oxa-7- azaspiro[2.5]oct-7- ylcarbonyl)propyl]-9H-purin-6- amine::US10221178, Compound 2-29
SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CCOC2(CC2)C1
InChI Key InChIKey=NYIVASXOKGPPTH-INIZCTEOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 361935
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 11nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair