BDBM361960 N-{(2S)-3-[(cis)-2,6- dimethylmorpholin-4-yl]-2- methyl-3-oxopropyl}-9-ethyl-8- (2-methylpyrimidin-5-yl)-9H- purin-6-amine::US10221178, Compound 2-54

SMILES CCn1c(nc2c(NC[C@H](C)C(=O)N3C[C@H](C)O[C@H](C)C3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=MXYRTYXPFVRTCC-SOUVJXGZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361960   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361960(N-{(2S)-3-[(cis)-2,6- dimethylmorpholin-4-yl]-2- m...)
Affinity DataIC50:  250nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent