BDBM361960 N-{(2S)-3-[(cis)-2,6- dimethylmorpholin-4-yl]-2- methyl-3-oxopropyl}-9-ethyl-8- (2-methylpyrimidin-5-yl)-9H- purin-6-amine::US10221178, Compound 2-54
SMILES CCn1c(nc2c(NC[C@H](C)C(=O)N3C[C@H](C)O[C@H](C)C3)ncnc12)-c1cnc(C)nc1
InChI Key InChIKey=MXYRTYXPFVRTCC-SOUVJXGZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 361960
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 250nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair