BDBM361963 N-[(1-{[(cis)-2,6- dimethylmorpholin-4- yl]carbonyl}cyclopropyl)methyl]- 9-ethyl-8-(2-methylpyrimidin-5- yl)-9H-purin-6-amine::US10221178, Compound 2-57
SMILES CCn1c(nc2c(NCC3(CC3)C(=O)N3C[C@H](C)O[C@H](C)C3)ncnc12)-c1cnc(C)nc1
InChI Key InChIKey=FSLOORZGHCSMOF-GASCZTMLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 361963
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 24nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair