BDBM362377 N-(3-(3-(3-(N,N-dimethylsulfamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)acrylamide ::US9834551, Example 34

SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1c[nH]c2ncc(cc12)-c1cccc(NC(=O)C=C)c1

InChI Key InChIKey=HXZVCUULXNINJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362377   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362377(N-(3-(3-(3-(N,N-dimethylsulfamoyl)phenyl)-1H-pyrro...)
Affinity DataIC50: >100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362377(N-(3-(3-(3-(N,N-dimethylsulfamoyl)phenyl)-1H-pyrro...)
Affinity DataIC50: >100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent