BDBM362912 (R)-2-(-1-ethyl-2-((trans-4-(trifluoromethyl)cyclohexyl)methyl)isoindoline-5-carboxamido)-2-(4-(ethylsulfonyl)phenyl)ethyl carbamate (24a and 24b)::US9845308, Example 24a

SMILES CC[C@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(ccc12)C(=O)N[C@@H](COC(N)=O)c1ccc(cc1)S(=O)(=O)CC

InChI Key InChIKey=ILHHFHNFZHZTJN-DKNHICIASA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362912   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362912((R)-2-(-1-ethyl-2-((trans-4-(trifluoromethyl)cyclo...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent