BDBM362923 (S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-1-isopropyl-2-((2-(trifluoromethyl)-1,3-dioxan-5-yl)methyl)isoindoline-5-carboxamide (32a and 32b)::US9845308, Example 32a::US9845308, Example 32b

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3[C@H](C(C)C)N(C[C@H]4CO[C@H](OC4)C(F)(F)F)Cc3c2)nc1

InChI Key InChIKey=BIXXDYNGOZGYAH-DQXHVOOISA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362923   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362923((S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-1-is...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362923((S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-1-is...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent