BDBM362928 US9849138, 3

SMILES CN1c2cccc(Cl)c2C(=O)NC(Cc2ccc(cc2)-c2ccncc2)C1=O

InChI Key InChIKey=ZTKDYYOUMRBNMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362928   

TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM362928(US9849138, 3)
Affinity DataIC50:  860nMAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM362928(US9849138, 3)
Affinity DataIC50: >3.00E+7nMAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent