BDBM363287 (R)-2-((5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)amino)-3-(thiazol-4-yl)propanoic acid::US9850225, Example 1206

SMILES Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN[C@H](Cc3cscn3)C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1

InChI Key InChIKey=VCSPNHIEPIAAIU-JGCGQSQUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363287   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363287((R)-2-((5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent