BDBM36344 CID24762174::{3-[2-trans-(4-Amino-cyclohexylamino)-9-phenyl-9H-purin-6-ylamino]-phenyl}-(4-methyl-piperazin-1-yl)-methanone, 12

SMILES CN1CCN(CC1)C(=O)c1cccc(Nc2nc(N[C@H]3CC[C@H](N)CC3)nc3n(cnc23)-c2ccccc2)c1

InChI Key InChIKey=KUYLQEGGVXKEJI-HZCBDIJESA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36344   

TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
The Scripps Research Institute

LigandPNGBDBM36344(CID24762174 | {3-[2-trans-(4-Amino-cyclohexylamino...)
Affinity DataEC50:  1.30E+3nMpH: 7.5 T: 2°CAssay Description:This parasite proliferation assay, a modification of published DNA intercalating fluorescent dye-based assay, was adapted to 384-well plate format an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
The Scripps Research Institute

LigandPNGBDBM36344(CID24762174 | {3-[2-trans-(4-Amino-cyclohexylamino...)
Affinity DataIC50:  6.87E+3nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed