BDBM363883 2-Ethyl-N-[(4-ethylphenyl)methyl]-6,7-dimethoxy-1-oxo-isoquinoline-4-carboxamide::US9856220, Example 313

SMILES CCc1ccc(CNC(=O)c2cn(CC)c(=O)c3cc(OC)c(OC)cc23)cc1

InChI Key InChIKey=NBQXPSPFEQPQDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363883   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
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US Patent
LigandPNGBDBM363883(2-Ethyl-N-[(4-ethylphenyl)methyl]-6,7-dimethoxy-1-...)
Affinity DataIC50:  350nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent