BDBM363930 6-[3-(2,4-dimethylpyrazol-3-yl)-1-piperidyl]pyrido[3,2-d]pyrimidin-4-amine::US9855269, Compound 173::US9855269, Compound 175

SMILES Cc1cnn(C)c1C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=FIWDDEYIMXFYTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363930   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM363930(6-[3-(2,4-dimethylpyrazol-3-yl)-1-piperidyl]pyrido...)
Affinity DataIC50:  1.80E+3nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM363930(6-[3-(2,4-dimethylpyrazol-3-yl)-1-piperidyl]pyrido...)
Affinity DataIC50:  93.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent