BDBM36395 5-Fluoro-2-thiophen-2-yl-1,2-dihydroquinazolin-4-amine, 1::CID21192814

SMILES NC1=NC(Nc2cccc(F)c12)c1cccs1

InChI Key InChIKey=OGKZGPSVQKXXOY-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36395   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36395(5-Fluoro-2-thiophen-2-yl-1,2-dihydroquinazolin-4-a...)
Affinity DataIC50:  10nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36395(5-Fluoro-2-thiophen-2-yl-1,2-dihydroquinazolin-4-a...)
Affinity DataIC50:  1.00E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36395(5-Fluoro-2-thiophen-2-yl-1,2-dihydroquinazolin-4-a...)
Affinity DataIC50:  2.50E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed