BDBM36408 1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, PP494::CID24905153
SMILES COc1ccc(cc1OC)-c1nn(C2CCC2)c2ncnc(N)c12
InChI Key InChIKey=ITOYZJGFTNTKKR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 36408
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta isoform(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/delta isoform(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta isoform(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 72nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Serine/threonine-protein kinase mTOR(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Platelet-derived growth factor receptor beta [525-1106] (Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 170nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Tyrosine-protein kinase HCK(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 130nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Proto-oncogene tyrosine-protein kinase Src(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 170nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Proto-oncogene tyrosine-protein kinase Src(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 3.00E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Vascular endothelial growth factor receptor 2(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 7.00E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Receptor protein-tyrosine kinase(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 2.30E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
TargetEphrin type-B receptor 4/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 1.40E+3nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 340nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair