BDBM364374 US10913711, Compound 2a::US11555013, Compound 2a::US9862679, Compound 2a

SMILES NC(=O)CSC(c1ccccc1)c1ccccc1

InChI Key InChIKey=HCRQRIFRHGPWBH-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 364374   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.24E+4nMAssay Description:Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.27E+4nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.27E+4nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.27E+4nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.27E+4nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.27E+4nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.27E+4nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi:  1.45E+4nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat brain SERT after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuroepithelial cell-transforming 1(Rat)
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi: >1.00E+5nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi: >1.00E+5nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM364374(US10913711, Compound 2a | US11555013, Compound 2a ...)
Affinity DataKi: >1.00E+5nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
In DepthDetails US Patent