BDBM364474 N-[6-(1-hydroxy-1-methylethyl)-2- phenyl-2H-pyrazolo[4,3-b]pyridin- 3-yl]-3-(1-methyl-1H-pyrazol-3-yl)- 4-(trifluoromethyl)benzamide::US9862707, Example 48::US9862707, Example 49
SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1n(nc2cc(cnc12)C(C)(C)O)-c1ccccc1
InChI Key InChIKey=ZFLNPQMSUGXZTP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 364474
Affinity DataIC50: 4.60nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair